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KMID : 0364219960390030299
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Korean Journal of Zoology
1996 Volume.39 No. 3 p.299 ~ p.306
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Effects of Antimetabolite 6-Aminonicotinamide on Levels of Free Amino Acids in Various Tissues of Quail
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Mok Chang-Soo
Kim Jae-Young
Shin Sook
Park In-Kook
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Abstract
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The effects of antimetabolite 6-aminonicotinamide on levels of soluble proteins, free amino acids and protease activity in various tissues of quail have been in vestigated. The levels of soluble proteins m liver, heart and pectoral muscle were markedly lowered and the specific activity of protease in kidney and pectoral muscle was markedly increased. The concentrations of aspartic acid / asparagine, alanine, valine, methionine, isoleucine, leucine and lysine in the liver were markedly increased. En the kidney the concentrations of aspartic acid I asparagine, arginine, threonine, alanine, proline and lysine were markedly increased but those of glutamic acid I glutamine were decreased. The concentrations of glutamic acid / glutamine and serine in the heart were reduced but those in glycine and methionine were increased. In the pectoral muscle the concentration of arginine was decreased but the concentration of alanine and threonine was increased. The overall results suggest that antimetabolite 6-aminonicotinamide may act to enhance concentrations of amino acids related to the generation of energy and to depress the biosynthesis of some specific amino acids.
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KEYWORD
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Antimetabolite, 6-Aminonicotinamide, Free Amino Acid, Quail
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